Open AccessAnalysis of Different Data Sets of the Same Clinical Trial May Yield Different Results
Author(s) -
Emin Mehmet Yusuf
Publication year - 2019
Publication title -
annals of advanced biomedical sciences
Language(s) - English
Resource type - Journals
ISSN - 2641-9459
DOI - 10.23880/aabsc-16000135
Subject(s) - randomized controlled trial , clinical trial , outcome (game theory) , protocol (science) , statistics , n of 1 trial , medicine , data mining , mathematics , computer science , alternative medicine , mathematical economics , pathology
In a randomized clinical trial (RCT), analysis of different data sets of the same clinical trial may change the meaningfulness of the difference between the study groups depending on which data sets are compared. Possible data sets are intention to treat (ITT), per protocol or on treatment (PP), as treated (AT). The specific conditions that may cause the greatest likelihood of affecting the outcome, depending on the choice of data sets compared should be further investigated.