Open AccessGeneral anesthesia in early childhood and possible association with autism: a population-based matched cohort study
Author(s) -
Andreas Pikwer,
Bei Yang,
Malin Granström,
Niklas Mattsson,
Omid Sadr–Azodi
Publication year - 2023
Publication title -
minerva anestesiologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.558
H-Index - 59
eISSN - 1827-1596
pISSN - 0375-9393
DOI - 10.23736/s0375-9393.22.16543-0
Subject(s) - autism , medicine , autism spectrum disorder , poisson regression , relative risk , population , cohort , pediatrics , cohort study , anesthesia , confidence interval , psychiatry , environmental health
In experimental animal studies, exposure to general anesthesia in early childhood may results in changes in infant brain morphology and behavior, potentially leading to the development of autistic behaviors in the long-term. However, in clinical studies the role of exposure to general anesthesia in early childhood and the risk of autism is unknown.