Open AccessEncapsulation of a bioactive steroid in apolymer matrix
Author(s) -
Ana Karelia Collado,
G. Hernandez,
V. Morejon,
Francisco Coll,
Carlos Péniche
Publication year - 2017
Publication title -
materials and devices
Language(s) - English
Resource type - Journals
ISSN - 2495-3911
DOI - 10.23647/ca.md20171505
Subject(s) - chitosan , biocompatibility , chitin , active ingredient , chemistry , spray drying , solubility , ingredient , biodegradation , natural polymers , polymer , food science , chromatography , pharmacology , biochemistry , biology , organic chemistry
DI-31 is a synthetic analog of brasinosteroids (ABR), the active ingredient (PA) of Biobras, a plantgrowth stimulant, which has shown positive impact on Cuban agriculture, especially in rice cultivation. However, ithas the drawback of having low solubility in water and being rapidly metabolized by the plants. An alternative toovercome these limitations is its micro-encapsulation in a polymer matrix. Chitosan (CHI) has been investigatedas an excellent candidate for microencapsulation of DI-31. Chitosan (CHI) is a natural polysaccharide obtainedfrom chitin extracted from exoesqueleton of crustaceans, which increases resistance of the plants to the attack ofpests and promotes the yield of the crops, also possesses excellent biocompatibility, biodegradability andmucoadhesivity, also inducing the defense of the plants against the attack of different pathogens. # polymer_matrix #chitosan #microparticles #spray_drying #DI-31