Open AccessA Case of Anaphylaxis in Which a Basophil Activation Test Was Used to Identify the Suspected Agent
Author(s) -
Takashi Goto,
Shigenari Hayashi,
Hiroko Tsugane,
Mitsuo Iinuma,
Shunsuke Sakurai
Publication year - 2020
Publication title -
anesthesia progress
Language(s) - English
Resource type - Journals
eISSN - 1878-7177
pISSN - 0003-3006
DOI - 10.2344/anpr-67-03-05
Subject(s) - basophil activation , anaphylaxis , medicine , anaphylactic reaction , dipstick , dermatology , etiology , test (biology) , allergy , immunology , basophil , intensive care medicine , immunoglobulin e , biology , urine , paleontology , antibody
This is a case report of anaphylaxis in which the basophil activation test (BAT) was used to identify the etiological agent. Although skin tests are considered the most effective methods for identifying anaphylactic triggers, the test itself presents a risk of inducing anaphylaxis. The BAT is advantageous because of its inherent lack of risk, high sensitivity and specificity to identify the suspected anaphylactic agents, and diagnostic accuracy comparable to conventional skin testing. Therefore, in the future, the BAT is likely to become the preferred test for the detection of allergens over conventional skin tests.