Open AccessFatigue is Associated with Reduced Participation and Health-Related Quality of Life Five Years After Perimesencephalic Subarachnoid Haemorrhage: A Multicentre Cross-Sectional Study
Author(s) -
Elisabeth A De Vries,
Wendy Boerboom,
Rita J G van den BergEmons,
Fop van Kooten,
Johanna M. A. VisserMeily,
Gerard M. Ribbers,
Majanka H. Heijenbrok–Kal
Publication year - 2022
Publication title -
journal of rehabilitation medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.893
H-Index - 96
eISSN - 1651-2081
pISSN - 1650-1977
DOI - 10.2340/jrm.v54.212
Subject(s) - medicine , anxiety , quality of life (healthcare) , hospital anxiety and depression scale , coping (psychology) , physical therapy , depression (economics) , cross sectional study , odds ratio , rehabilitation , confidence interval , psychiatry , nursing , pathology , economics , macroeconomics
Objective: To determine whether fatigue is associated with participation and health-related quality of life 5 years after perimesencephalic subarachnoid haemorrhage.Design: Multicentre cross-sectional study.Subjects: Forty-six patients with perimesencephalic subarachnoid haemorrhage.Methods: Fatigue was assessed with the Fatigue Severity Scale, participation (frequency, restrictions, satisfaction) with the Utrecht Scale forEvaluation of Rehabilitation-Participation, healthrelated quality of life with the Stroke-Specific Quality of Life Scale-12, symptoms of depression and anxiety with the Hospital Anxiety and Depression Scale, and coping with the Coping Inventory forStressful Situations. Results: A total of 46 patients were included (63% men, mean age 50.4±9.4 years), a mean of 4.7±1.6 years after onset of perimesencephalic subarachnoid haemorrhage. Fatigued patients (33%) had worse participation (p < 0.01) and health-related quality of life (p < 0.001) than non-fatigued patients, and more often had hypertension, depression, anxiety and emotion-oriented coping (p < 0.05). Fatigue severity was inversely and independently (p < 0.005) associated with participation frequency (B = –3.62), satisfaction (B = –4.54), having restrictions (odds ratio = 2.48, confidence interval 1.079–5.685), and health-related quality of life (B = –0.19), adjusted for depression, anxiety, and/or hypertension.Conclusion: Five years after perimesencephalic subarachnoid haemorrhage, one-third of patients still reported fatigue, associated with worse participation and health-related quality of life. Future studies should examine whether these patients may benefit from rehabilitation aimed at fatigue.