A Nationwide Observational Study of Chlamydia trachomatis Infections in Denmark during the COVID-19 Pandemic | Zendy

Paula L. Hedley | Zendy; Steen Hoffmann | Zendy; Ulrik LaustenThomsen | Zendy; Marianne Voldstedlund | Zendy; Karsten Bjerre | Zendy; Anders Hviid | Zendy; Lone Krebs | Zendy; Jørgen Skov Jensen | Zendy; Michael Christiansen | Zendy

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A Nationwide Observational Study of Chlamydia trachomatis Infections in Denmark during the COVID-19 Pandemic

Author(s) -

Paula L. Hedley,

Steen Hoffmann,

Ulrik LaustenThomsen,

Marianne Voldstedlund,

Karsten Bjerre,

Anders Hviid,

Lone Krebs,

Jørgen Skov Jensen,

Michael Christiansen

Publication year - 2022

Publication title -

acta dermato venereologica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.982

H-Index - 83

eISSN - 1651-2057

pISSN - 0001-5555

DOI - 10.2340/actadv.v102.2324

Subject(s) - chlamydia trachomatis , confidence interval , medicine , chlamydia , incidence (geometry) , poisson regression , danish , pandemic , covid-19 , population , observational study , rate ratio , epidemiology , logistic regression , demography , virology , immunology , environmental health , infectious disease (medical specialty) , disease , linguistics , philosophy , physics , sociology , optics

The aim of this study was to determine whether COVID-19 restrictions had an impact on Chlamydia trachomatis infections compared with 2018 and 2019. A retrospective nationwide observational study was performed using monthly incidences of laboratory-confirmed chlamydia cases and number of tests, obtained from Danish national surveillance data. Testing rates and positivity rates were compared using Poisson and logistic regression. The first Danish COVID-19 lockdown (12 March to 14 April 2020) resulted in a reduction in the number of chlamydia tests performed (rate ratio 0.72, 95% confidence interval (95% CI) 0.71–0.73) and a consequent reduction in the number of laboratory-identified cases (66.5 vs 88.3 per 100,000 during the same period in 2018 to 2019). This period was followed by a return of testing and test positivity close to the level seen in 2018 to 2019. The second Danish COVID-19 lockdown (17 December to 31 March 2021) resulted in crude incidence rates of laboratory-confirmed chlamydia infection that were similar to the crude incidence rates seen during same period in 2018 to 2019. In conclusion, the Danish COVID-19 restrictions have had negligible effects on laboratory-confirmed C. trachomatis transmission.

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