Insulin-Like Growth Factor Binding Protein 2 (IGFBP-2) and the Risk of Developing Type 2 Diabetes
Author(s) -
Clemens Wittenbecher,
Meriem Ouni,
Olga Kuxhaus,
Markus Jähnert,
Pascal Gottmann,
Andrea Teichmann,
Karina Meidtner,
Jennifer Kriebel,
Harald Grallert,
Tobias Pischon,
Heiner Boeing,
Matthias B. Schulze,
Annette Schürmann
Publication year - 2018
Publication title -
diabetes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.219
H-Index - 330
eISSN - 1939-327X
pISSN - 0012-1797
DOI - 10.2337/db18-0620
Subject(s) - type 2 diabetes , diabetes mellitus , medicine , endocrinology , risk factor , insulin like growth factor binding protein , population , insulin , growth factor , insulin like growth factor , biology , environmental health , receptor
Recent studies suggest that insulin-like growth factor binding protein 2 (IGFBP-2) may protect against type 2 diabetes, but population-based human studies are scarce. We aimed to investigate the prospective association of circulating IGFBP-2 concentrations and of differential methylation in the IGFBP-2 gene with type 2 diabetes risk.
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