Open AccessOverexpression of osteoprotegerin promotes preosteoblast differentiation to mature osteoblasts
Author(s) -
Hongyou Yu,
Paul de Vos,
Yijin Ren
Publication year - 2011
Publication title -
the angle orthodontist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 86
eISSN - 1945-7103
pISSN - 0003-3219
DOI - 10.2319/050210-238.1
Subject(s) - osteoprotegerin , runx2 , transfection , osteoblast , western blot , downregulation and upregulation , chemistry , alkaline phosphatase , reverse transcription polymerase chain reaction , microbiology and biotechnology , cell sorting , real time polymerase chain reaction , cell culture , cell , messenger rna , biology , enzyme , in vitro , gene , biochemistry , activator (genetics) , genetics
The hypothesis of the present study is that overexpression of osteoprotegerin (OPG) promotes preosteoblast maturation.