Open Access2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) as a Potent and Persistent Thyroxine Agonist: A Mechanistic Model for Toxicity Based on Molecular Reactivity
Author(s) -
James D. McKinney,
J. Fawkes,
S. Jordan,
K. Chae,
S. Oatley,
R. E. Coleman,
W. Briner
Publication year - 1985
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.2307/3430061
Subject(s) - chemistry , toxicity , hormone , mechanism of action , receptor , nuclear receptor , agonist , thyroid hormone receptor , hormone receptor , medicine , pharmacology , endocrinology , biology , biochemistry , in vitro , organic chemistry , cancer , breast cancer , transcription factor , gene