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Some topics of current interest in clinical trials
Author(s) -
Armitage Peter
Publication year - 1992
Publication title -
canadian journal of statistics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.804
H-Index - 51
eISSN - 1708-945X
pISSN - 0319-5724
DOI - 10.2307/3315570
Subject(s) - clinical trial , variety (cybernetics) , categorical variable , replication (statistics) , bayesian probability , computer science , management science , medical physics , medicine , artificial intelligence , machine learning , engineering , pathology , virology
After a short review of the development of the modern approach to the design of clinical trials, attention is focused on the wide variety of trials, their ethical constraints, the criteria for stopping trials, and the possible use of Bayesian methods. Brief discussions are then presented of two specific topics: the analysis of categorical data, and the replication of trials with the consequent need for overviews.