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The Chance Occurrence of Substantial Initial Differences between Groups in Studies Based on Random Allocation
Author(s) -
Radhakrishna S.,
Sutherland Ian
Publication year - 1962
Publication title -
journal of the royal statistical society: series c (applied statistics)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.205
H-Index - 72
eISSN - 1467-9876
pISSN - 0035-9254
DOI - 10.2307/2985289
Subject(s) - statistics , mathematics , econometrics , computer science
When the merits of different treatments are being studied and subjects are allocated to the treatment groups at random, undesirably large initial differences between the groups sometimes occur. Incorrect conclusions may be drawn if these differences are ignored. In this paper the authors recommend the use of a statistical technique such as analysis of covariance or standardisation to adjust the results for pretreatment differences.