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Tissue Matching and Matchability in Kidney Transplantation
Author(s) -
Gilks Walter R.
Publication year - 1991
Publication title -
journal of the royal statistical society: series c (applied statistics)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.205
H-Index - 72
eISSN - 1467-9876
pISSN - 0035-9254
DOI - 10.2307/2347596
Subject(s) - matching (statistics) , kidney , computer science , medicine , pathology
SUMMARY Success in kidney transplantation depends on the degree of tissue matching between donor and recipient. The matchability of a patient is defined as the probability that the patient will be offered a well‐matched kidney from a random donor. Matchability depends on the patient's tissue type, but also depends on the tissue types of other patients awaiting kidney transplantation. A method of estimating matchability is proposed. By simulation, some possibilities for introducing a matchability criterion into the priority scheme for recipient selection are explored, to increase the numbers of patients receiving well‐matched kidneys and to provide a more equitable allocation of kidneys to matchability groups.