Open AccessOral candidiasis-adhesion of non-albicans Candida species
Author(s) -
B Marija Bokor-Bratic
Publication year - 2008
Publication title -
zbornik matice srpske za prirodne nauke
Language(s) - English
Resource type - Journals
eISSN - 2406-0828
pISSN - 0352-4906
DOI - 10.2298/zmspn0814069b
Subject(s) - candida albicans , microbiology and biotechnology , dentures , corpus albicans , colonisation , adhesion , biology , buccal administration , opportunistic pathogen , pathogenesis , fungal pathogen , stomatitis , pathogen , immunology , medicine , virulence , dentistry , colonization , dermatology , chemistry , bioinformatics , genetics , organic chemistry , gene
Oral candidiasis is an opportunistic infection caused primarily by Candida albicans. However, in recent years, species of non-albicans Candida have been implicated more frequently in mucosal infection. Candida species usually reside as commensal organisms and are part of normal oral microflora. Determining exactly how transformation from commensal to pathogen takes place and how it can be prevented is continuous challenge for clinical doctors. Candidal adherence to mucosal surfaces is considered as a critical initial step in the pathogenesis of oral candidiasis. Acrylic dentures, acting as reservoirs, play an important role in increasing the risk from Candida colonisation. Thus, this review discusses what is currently known about the adhesion of non-albicans Candida species of oral origin to buccal epithelial cells and denture acrylics