Open AccessGRACE, SYNTAX I and SYNTAX II scores as predictors of one-year MACE outcome in patients with myocardial infarction treated with percutaneous coronary intervention
Author(s) -
Aleksandar Davidović,
Dane Cvijanović,
Jelica Davidović,
Snežana Lazić,
Bratislav Lazić,
L Cucic,
Marija Milić,
Nataša Marković-Nikolić
Publication year - 2022
Publication title -
vojnosanitetski pregled
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.123
H-Index - 19
eISSN - 2406-0720
pISSN - 0042-8450
DOI - 10.2298/vsp200204055d
Subject(s) - mace , medicine , conventional pci , percutaneous coronary intervention , myocardial infarction , cardiology , syntax , natural language processing , computer science
Background/Aim. The fundamental objective of primary percutaneous coronary intervention (PKI) in myocardial infarction is to provide early, complete and sustained flow in the occluded artery that has led to myocardial ischemia or necrosis. The aim of this study was to determine the predictive power of a combination of GRACE, SYNTAX I, and SYNTAX II scores in predicting major cardiovascular adverse events and one-year mortality in patients with STEMI and NSTEMI myocardial infarction after primary PCI. Methods. Our study included 400 patients who had their first acute myocardial infarction and underwent percutaneous coronary intervention, treated and followed for one year at the Clinical Hospital Center Zvezdara at the Department of Interventional Cardiology. By monitoring the defined clinical parameters, a comparative analysis of risk scores was performed: GRACE, SYNTAX I and SYNTAX II, their sensitivity, specificity as well as predictive possibilities in predicting adverse outcomes were determined. Results. The incidence of major adverse cardiovascular outcomes in our sample was 12,8%. Patients with STEMI entity had significantly higher values of GRACE, SYNTAX I and SYNTAX II scores. The highest value for predicting the occurrence of major adverse cardiovascular outcomes was shown by the SYNTAX II score (score value 29,3) with a sensitivity of 88,2% and a specificity of 76,8%. The GRACE score is a significant predictor of SYNTAX I and SYNTAX II scores, a two-way correlation was observed between the high score values of all three scores. Conclusion. The presented scores for assessment of clinical and angiographic indicators, showed good predictive power in assessing the outcome of adverse cardiovascular events in both clinical entities of acute myocardial infarction during one year follow up. By using the proposed scores to assess adverse outcomes, we can single out high-risk patients in order to prevent outcomes and reduce mortality. This suggests its suitability for clinical use in this patient population.