Staphylococcus aureus methicillin-resistance mechanisms | Zendy

Ljiljana Petrovic-Jeremic | Zendy; N Kuljić-Kapulica | Zendy; Veljko Mirović | Zendy; Branislava Kocić | Zendy

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Staphylococcus aureus methicillin-resistance mechanisms

Author(s) -

Ljiljana Petrovic-Jeremic,

N Kuljić-Kapulica,

Veljko Mirović,

Branislava Kocić

Publication year - 2008

Publication title -

vojnosanitetski pregled

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.123

H-Index - 19

eISSN - 2406-0720

pISSN - 0042-8450

DOI - 10.2298/vsp0805377p

Subject(s) - cefoxitin , staphylococcus aureus , medicine , methicillin resistant staphylococcus aureus , microbiology and biotechnology , penicillin , antibiotics , vancomycin , staphylococcal infections , antibiotic resistance , biology , bacteria , genetics

In many hospitals in the world and in our country, the spread of methicillin-resistant Staphylococcus aureus (MRSA) is so wide that nowdays vancomycin is recommended for empiric treatment of staphylococcal life threatening infections (sepsis, pneumonia) instead of beta-lactam antibiotics. The aim of this study was to determine the production of beta-lactamases in hospital and community isolates of staphyloococus aureus, i.e. hospital associated MRSA (HA-MRSA) and community associated MRSA (CA-MRSA), the presence of homogeneous and heterogeneous type of methicillin resistance, and border-line resistance in Staphylococcus aureus (BORSA). The aim of this study was also to determine if there was a statistically significant difference between mechanisms of resistance in HA-MRSA and CA-MRSA.

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