Open AccessImportance of inflammation in arteriosclerotic plaque destabilization and rupture
Author(s) -
Vujadin Tatić,
Vladimir Kanjuh,
I Sasa Rafajlovski,
Kristina Kostić,
Dušan Šuščević
Publication year - 2005
Publication title -
vojnosanitetski pregled
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.123
H-Index - 19
eISSN - 2406-0720
pISSN - 0042-8450
DOI - 10.2298/vsp0509649t
Subject(s) - arteriosclerosis , inflammation , pathology , coronary arteries , medicine , cd68 , trichrome , infiltration (hvac) , fibrous cap , artery , immunology , h&e stain , immunohistochemistry , physics , thermodynamics
Although Rudolf Virchow considered arteriosclerosis an inflammatory disease in his book Cellular Pathology publisched in 1858, the opinion that it was a degenerative arterial disease as a civilization disease prevailed. Nowadays, a great attention has been paid to the inflammatory process in the patogenesis of arteriosclerosis and particularly in the destabilization and rupture of plaque.