Significance of iron reduction for the therapy of chronic hepatitis C | Zendy

Darko Nožić | Zendy; Bela Balint | Zendy; Nebojša Stanković | Zendy; J Dimitrijević | Zendy; Goraesković | Zendy

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Significance of iron reduction for the therapy of chronic hepatitis C

Author(s) -

Darko Nožić,

Bela Balint,

Nebojša Stanković,

J Dimitrijević,

Goraesković

Publication year - 2005

Publication title -

vojnosanitetski pregled

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.123

H-Index - 19

eISSN - 2406-0720

pISSN - 0042-8450

DOI - 10.2298/vsp0502161n

Subject(s) - medicine , phlebotomy , ribavirin , chronic hepatitis , pegylated interferon , hepatitis c , gastroenterology , hepatitis c virus , immunology , hepatitis , viral hepatitis , interferon , virus

It has been established that many patients with chronic hepatitis C have elevated serum iron, feritin levels and iron deposites in the liver. Therefore, the liver damage due to hepatitis C virus may be aggravated with iron overload. In many studies higher levels of iron in the blood and the liver were connected with the decreased response to interferon-alfa therapy for chronic viral hepatitis C. Recent introduction of pegylated interferons plus ribavirin has improved the therapeutic response, so it is now possible to cure more than 50% of the patients.

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