Open AccessDisturbances of protein c activity in abdominal sepsis: Diagnostic and predictive importance
Author(s) -
Aleksandar P. Karamarković,
Darko Mirković,
Nebojša Stanković,
V.T. Nikolic,
Vasilije Jeremić,
Dejan V Radenković,
Branislav Stefanović
Publication year - 2004
Publication title -
vojnosanitetski pregled
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.123
H-Index - 19
eISSN - 2406-0720
pISSN - 0042-8450
DOI - 10.2298/vsp0406599k
Subject(s) - medicine , sepsis , gastroenterology , septic shock , peritonitis , systemic inflammatory response syndrome , c reactive protein , inflammation
Despite improved diagnostic modalities, potent antibiotics, modern intensive care, and aggressive surgical treatment, more than one third of patients still die of severe secondary peritonitis. Clinical difficulties in the treatment of abdominal sepsis were related to inherent problems of limited clinical signs and the rapid spread of infection. An inflammatory process is often well under way before the presence of clinical signs and symptoms of sepsis. The aim of this prospective study was to assess diagnostic and prognostic significance of protein C in abdominal sepsis.