Open AccessUmbilical metastasis (Sister Mary Joseph's nodule) diagnosed by fine-needle aspiration
Author(s) -
Željka Tatomirović,
Radojka Bokun,
Vesna Škuletić,
S Ilić,
Branka Roganović,
Dragan Milutinović
Publication year - 2004
Publication title -
vojnosanitetski pregled
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.123
H-Index - 19
eISSN - 2406-0720
pISSN - 0042-8450
DOI - 10.2298/vsp0405561t
Subject(s) - medicine , metastasis , sister , nodule (geology) , pathology , general surgery , biology , cancer , law , political science , paleontology
Sister Mary Joseph's nodule is the eponym for metastatic involvement of the umbilicus. This less common entity is the sign of disseminated malignant disease, mainly of digestive and gynecologic origin, and is associated with a poor prognosis. A case of Sister Mary Joseph's nodule in a 76-year-old woman in whom the umbilical metastasis was the first sign of malignant disease in presented. The diagnosis of metastatic adenocarcinoma was established by fine needle aspiration cytology of the umbilical nodule. Radiological and ultrasonographic investigation disclosed carcinoma of the gallbladder with pancreas, stomach, and colon invasion as well as peritoneal dissemination. The diagnosis was confirmed by exploratory laparatomy and histological examination of the excised umbilical nodule.