Open AccessComparison of two different protocols for the induction of maturation of human dendritic cells in vitro
Author(s) -
Miodrag Čolić,
Slavko Mojsilovic,
Bojan Pavlović,
Dragana Vučićević,
Ivana Majstorović,
Biljana Bufan,
Zorica Stojić-Vukanić,
Saša Vasilijić,
Dragana Vučević,
Sonja Gašić,
Bela Balint
Publication year - 2004
Publication title -
vojnosanitetski pregled
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.123
H-Index - 19
eISSN - 2406-0720
pISSN - 0042-8450
DOI - 10.2298/vsp0405471c
Subject(s) - proinflammatory cytokine , in vitro , flow cytometry , lipopolysaccharide , cd86 , tumor necrosis factor alpha , immunology , monocyte , dendritic cell , biology , microbiology and biotechnology , granulocyte macrophage colony stimulating factor , andrology , chemistry , cytokine , inflammation , immune system , medicine , t cell , biochemistry
Dendritic cells (DC) have been used for immunotherapy of malignant tumors, different kinds of infections, and other clinical conditions. For that purpose, optimal conditions for the generation of functionally mature DC in vitro are required. Two different protocols for the induction of maturation of monocyte-derived DC (MDDC) were compared in this study.