Open AccessPathophysiology, clinical manifestation and management of angioedema - our experience
Author(s) -
Aleksandra Aleksić,
M Bogić,
Vesna Tomić Spirić,
Aleksandra Perić-Popadić,
Dalibor Vranješ,
Borut Bosančić
Publication year - 2015
Publication title -
srpski arhiv za celokupno lekarstvo
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 17
eISSN - 2406-0895
pISSN - 0370-8179
DOI - 10.2298/sarh1510545a
Subject(s) - medicine , angioedema , larynx , laryngeal edema , hereditary angioedema , pharynx , intubation , retrospective cohort study , pathophysiology , dermatology , tracheotomy , otorhinolaryngology , airway obstruction , edema , surgery , airway
Angioedema is characterized by subcutaneous and/or submucosal swelling usually localized to the lips, eyelids, tongue, oral cavity, larynx and pharynx. Various types of angioedema, caused by different pathophysiologic mechanisms, can have the same or very similar clinical picture and require different diagnostic and therapeutic procedures. The immediate threat to life as a result of rapidly developed edema of the pharynx and larynx with airway obstruction requires endotracheal intubation or emergency tracheotomy. Standard therapy, which includes epinephrine, second-generation antihistamines and steroids, is not effective in the treatment of all types of angioedema.