Open AccessExamination of possible role of the chlamydial stress proteins in pathogenesis of ectopic pregnancy
Author(s) -
Maja Vivoda,
Biljana Arsić,
Eliana Garalejić,
Ivana Ćirković,
Slobodanka Djukić
Publication year - 2014
Publication title -
srpski arhiv za celokupno lekarstvo
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 17
eISSN - 2406-0895
pISSN - 0370-8179
DOI - 10.2298/sarh1402054v
Subject(s) - chlamydia trachomatis , ectopic pregnancy , medicine , pathogenesis , chlamydia , pregnancy , antibody , immunology , chlamydiaceae , immunofluorescence , biology , genetics
Chlamydia trachomatis infections are the most prevalent bacterial sexually transmitted infections recognized throughout the world. In the last few years, several studies have indicated that predisposition of C. trachomatis to persist within the host cell is recognized as a major factor in the pathogenesis of chlamydial infection. During persistent chlamydial infection, the stress protein hsp60 is synthesized continually as immunopathologic antigen. Antibodies to hsp60 are found in women with tubal occlusion, but these antibodies are not detected in women with the acute C. trachomatis infection, which indicates that hsp60 has an important role in pathogenesis of persistant chlamydial infection.