Open AccessThe efficacy and tolerability of allopurinol dose escalation in patients with gout
Author(s) -
Marija Radak-Perović,
Mirjana Zlatković-Švenda
Publication year - 2013
Publication title -
srpski arhiv za celokupno lekarstvo
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 17
eISSN - 2406-0895
pISSN - 0370-8179
DOI - 10.2298/sarh1306333r
Subject(s) - medicine , allopurinol , gout , tolerability , hyperuricemia , uric acid , febuxostat , adverse effect , gastroenterology , surgery
Allopurinol is still the drug of choice for the long-term control of hyperuricemia in patients with gout. Objective The aim of the study was to investigate the efficacy and tolerability of different allopurinol doses used in order to attain a target serum uric acid concentration (SUc) of <6 mg/dl (360 micromol/L).