Open AccessDetection of laboratory biomarkes in haematological and pulmonology patients at high risk for aspergillosis
Author(s) -
Eleonora Ratkov,
Ana Vidović,
Predrag Minić,
Dragana Janić,
Sandra Šipetić-Grujičić,
Aleksandar Džamić,
Valentina Arsić-Arsenijević
Publication year - 2012
Publication title -
srpski arhiv za celokupno lekarstvo
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 17
eISSN - 2406-0895
pISSN - 0370-8179
DOI - 10.2298/sarh1206290r
Subject(s) - galactomannan , aspergillosis , medicine , pulmonology , hematology , aspergillus , incidence (geometry) , medical microbiology , immunosuppression , aspergillus fumigatus , immunology , intensive care medicine , microbiology and biotechnology , biology , physics , optics
During the past decades a dramatic increase in the incidence of invasive fungal diseases, especially invasive aspergillosis has been observed. Undiagnosed and diagnosed late invasive aspergillosis is followed by lethality of up to 90%. Detection of early laboratory biomarkers (galactomannan and anti-Aspergillus antibodies) contributes to early diagnosis and is used for screening, as well as for monitoring therapy of aspergillosis.