Prognostic significance of new biological markers in chronic lymphocytic leukaemia | Zendy

Danijela Leković | Zendy; Biljana Mihaljević | Zendy; Nada KraguljacKurtović | Zendy; Maja PerunicicJovanovic | Zendy; Andrija Bogdanović | Zendy; Milica Čolović | Zendy; Mirjana Gotić | Zendy

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Prognostic significance of new biological markers in chronic lymphocytic leukaemia

Author(s) -

Danijela Leković,

Biljana Mihaljević,

Nada KraguljacKurtović,

Maja PerunicicJovanovic,

Andrija Bogdanović,

Milica Čolović,

Mirjana Gotić

Publication year - 2011

Publication title -

srpski arhiv za celokupno lekarstvo

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.135

H-Index - 17

eISSN - 2406-0895

pISSN - 0370-8179

DOI - 10.2298/sarh1112753l

Subject(s) - medicine , cd38 , antigen , immunohistochemistry , clinical significance , beta 2 microglobulin , bone marrow , stage (stratigraphy) , pathology , disease , oncology , gastroenterology , immunology , cd34 , paleontology , genetics , stem cell , biology

Chronic lymphocytic leukaemia is a disease with heterogeneous clinical course and outcome. Some patients have a progressive course of the disease and require therapy immediately after the diagnosis, while others have a stable form without the need for treatment. Recently, two new biological markers, the expression of CD38 antigen and ZAP-70 have shown independent significance in the prognosis in CLL patients.

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