Open AccessDiffuse large cell lymphoma and colon adenocarcinoma in patient with Waldenström’s macroglobulinaemia
Author(s) -
Milica Radojković,
Slavica Ristić,
Nataša Čolović,
Vesna ČemerikićMartinović,
Milica Čolović
Publication year - 2011
Publication title -
srpski arhiv za celokupno lekarstvo
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 17
eISSN - 2406-0895
pISSN - 0370-8179
DOI - 10.2298/sarh1102095r
Subject(s) - medicine , lymphoplasmacytic lymphoma , waldenstrom macroglobulinemia , lymphoma , macroglobulinemia , lymphoproliferative disorders , monoclonal gammopathy of undetermined significance , pathology , adenocarcinoma , gammopathy , malignancy , mantle cell lymphoma , monoclonal , multiple myeloma , immunology , cancer , antibody , monoclonal antibody
Waldenström's macroglobulinaemia is a rare B cell lymphoproliferative disorder characterized by lymphoplasmocyte bone marrow infiltration and monoclonal IgM gammopathy. In the majority of cases, Waldenström's macroglobulinaemia is a chronic disease with variable course. Therapy consists of alkylating agents, purine analogs and antiCD20 monoclonal antibody. In the literature, there have been descriptions of rare cases of progression of Waldenström's macroglobulinaemia to aggressive lymphoma, as well as secondary carcinoma in the patients after treatment of macroglobulinaemia.