Open AccessCholestatic hepatitis associated with nimesulide: A case report
Author(s) -
Snežana Lukić,
Miodrag Krstić,
Nemanja Damjanov,
Ivan Boričić,
D. S. Popović,
Srdjan Djuranović,
Nada Kovačević,
Nada Tomanović
Publication year - 2009
Publication title -
srpski arhiv za celokupno lekarstvo
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 17
eISSN - 2406-0895
pISSN - 0370-8179
DOI - 10.2298/sarh0910550l
Subject(s) - nimesulide , medicine , hepatitis , acute hepatitis , hepatology , gastroenterology , surgery , pediatrics
A toxic effect of drugs, including non-steroidal anti-inflammatory drugs, may be one of aetiological factors for the occurrence of acute hepatitis. Nimesulide is a selective cyclooxygenase-2 inhibitor, whose adverse effects on the liver range from acute hepatitis to more serious conditions, involving the development of acute liver failure and fatal outcome.