Open AccessRecombinant activated factor VII and intraoperative use of cell saver in neurosurgical treatment of arteriovenal malformation
Author(s) -
Vesovak,
B Milica Petrovic,
Branko Čalija,
Ljiljana Mitov,
Zoran Rančić
Publication year - 2008
Publication title -
srpski arhiv za celokupno lekarstvo
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 17
eISSN - 2406-0895
pISSN - 0370-8179
DOI - 10.2298/sarh08s3210n
Subject(s) - medicine , arteriovenous malformation , surgery , recombinant dna , endovascular treatment , anesthesia , aneurysm , biochemistry , chemistry , gene
. Arteriovenous (AV) malformation of brain causes abundant intraoperative bleedings, because of increased blood flow, which complicates operative treatment. The use of cell saver for intraoperative salvage of blood and recombinant activated factor VII (rFVIIa ) significantly reduces complications during operative treatment. CASE OUTLINE. We present a 29-year old male patient with AV malformation of the 4th degree on Spetzler-Martin scale. Because of the possibility of abundant bleeding, a cell saver (Sequestra 1000 Metronic, USA) was used, and to achieve and control adequate haemostasis, we used rFVIIa. CONCLUSION. The use of cell saver for intraoperative blood salvage and rFVIIa proved successful in operative treatment of AV malformation of 4th degree.