Open AccessUnusual biological behavior of femoral liposarcoma
Author(s) -
M. Stojanovic,
Branislav Goldner,
Spasenija Djukic
Publication year - 2007
Publication title -
srpski arhiv za celokupno lekarstvo
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 17
eISSN - 2406-0895
pISSN - 0370-8179
DOI - 10.2298/sarh0708468s
Subject(s) - medicine , liposarcoma , malignancy , radiation therapy , amputation , surgery , femur , pelvis , soft tissue , chemotherapy , sarcoma , lymph , soft tissue sarcoma , radiology , pathology
Liposarcoma of a bone is a very rare tumour of the fatty marrow, originating from lipoblasts. Its frequency is 1:1000 of all bone tumours. The long bones and the lower extremities are predominantly affected, equally in males and females between 30 and 70 years of age. In the estimation of its biological behaviour, histological graduation (G), the surgical localization of the tumour (T) and the presence or absence of metastases (M), are very important. A tumour with low grade differentiation, with transosseal propagation and metastases, has a poor prognosis. Surgical resection-amputation, chemotherapy and radiotherapy are the therapeutic methods of choice.