
The value of corticotropin-releasing hormone (CRH) test for differential diagnosis of Cushing’s syndrome
Author(s) -
Zorana Penezić,
Miloš Žarković,
Svetlana Vujović,
Miomira Ivović,
Biljana Beleslin,
Jasmina Ćirić,
Milka Drezgić
Publication year - 2007
Publication title -
srpski arhiv za celokupno lekarstvo
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 17
eISSN - 2406-0895
pISSN - 0370-8179
DOI - 10.2298/sarh0702031p
Subject(s) - medicine , endocrinology , basal (medicine) , differential diagnosis , pituitary adenoma , receiver operating characteristic , cushing syndrome , adrenal adenoma , area under the curve , adrenocorticotropic hormone , adenoma , hormone , pathology , diabetes mellitus
Diagnosis and differential diagnosis of Cushing's syndrome (CS) remain considerable challenge in endocrinology. For more than 20 years, CRH has been widely used as differential diagnostic test. Following the CRH administration, the majority of patients with ACTH secreting pituitary adenoma show a significant rise of plasma cortisol and ACTH, whereas those with ectopic ACTH secretion characteristically do not.