Open AccessComparison of three diagnostic methods to confirm Helicobacter pylori infection
Author(s) -
Nataša Opavski,
Milan Špuran,
Slobodanka Djukić,
Vera Mijač,
Lazar Ranin
Publication year - 2007
Publication title -
srpski arhiv za celokupno lekarstvo
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 17
eISSN - 2406-0895
pISSN - 0370-8179
DOI - 10.2298/sarh0702026o
Subject(s) - medicine , helicobacter pylori , helicobacter pylori infection , helicobacter infections , microbiology and biotechnology , gastroenterology , biology
Helicobacterpylori induces gastric inflammation in host and such gastritis increases the risk of gastric and duodenal ulceration as well as adenocarcinoma. Because peptic ulcer disease is the major cause of morbidity, accurate diagnosis of H. pylori infection is very important. Unfortunately, there is no gold standard among diagnostic tests for Helicobacter infections. If gastroscopy is performed, histopathology and urease test are the most often used. Still, culturing of this bacterium is essential for drug susceptibility testing and analysis of virulence factors.