Open AccessNew strategies in multiple organ dysfunction syndrometherapy for sepsis
Author(s) -
Maja Šurbatović,
Sonja Radaković,
Krsta Jovanović,
Predrag Romić
Publication year - 2005
Publication title -
srpski arhiv za celokupno lekarstvo
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 17
eISSN - 2406-0895
pISSN - 0370-8179
DOI - 10.2298/sarh0508379s
Subject(s) - medicine , multiple organ dysfunction syndrome , sepsis , drotrecogin alfa , intensive care medicine , organ dysfunction , early goal directed therapy , intensive care , severe sepsis , septic shock
Despite more than 20 years of extensive research, sepsis and/or trauma induced multiple organ dysfunction syndrome (MODS) remain the chief cause of death in intensive care units, with mortality rates between 30% and 80%. Early goal-directed therapy (EGDT), use of drotrecogin alfa (activated), tight control of hyperglycaemia, and adrenal replacement therapy (low doses of corticosteroids), all constitute new treatment strategies. In future, a combination of therapies should be individually adjusted for each patient.