Open AccessMatematics model in the prediction of hyperlipidemia's influence on the thickness of intima-media complex of A. Carotis communis as the index of atherosclerosis
Author(s) -
Marija Nedeljkovic,
B Petrović,
Dragan Djuric
Publication year - 2002
Publication title -
srpski arhiv za celokupno lekarstvo
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 17
eISSN - 2406-0895
pISSN - 0370-8179
DOI - 10.2298/sarh0210301n
Subject(s) - medicine , hyperlipidemia , secondary prevention , index (typography) , primary prevention , coronary atherosclerosis , cardiology , coronary heart disease , endocrinology , disease , world wide web , computer science , diabetes mellitus
The growth of intima media complex is widely accepted parameter in studies that are in relation to the process of atherosclerosis. Increased value of intima-media thickness (IMT) a. carotis communis is the incontestable index of atherosclerosis process in regard to distinct vascular spheres and wider cardiovascular risk. Hypercholesterolemia as the well-known promoter of atherogenesis influence on the increase of IMT. It is established that there is a highly valuable connection (p < 0.001) between the levels of cholesterol and the thickness of IMT. It is also observed a highly significant linear and cubic correlation between the cholesterol and IMT. Concerning the relationship between trigliceride and IMT, it stands out as the highly relevant (R = 0.42; p < 0.001) but the coefficient of correlation is fewer than cholesterol (R = 0.56). Increased value of cholesterol and triglicerides exerts influence on IMT of a. carotis communis simultaneously which leads to highly consequential equation: IMT = 0.005 x TG-0.008 x Chol + 0.28. This mathematics model can be noteworthy if one anticipates effects of primary and secondary prevention.