Open AccessDiffusion disorder in liver cirrhosis
Author(s) -
Cjorće Tulafić,
Mirjana Perišić,
P Rebić
Publication year - 2002
Publication title -
srpski arhiv za celokupno lekarstvo
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 17
eISSN - 2406-0895
pISSN - 0370-8179
DOI - 10.2298/sarh0204068c
Subject(s) - medicine , cirrhosis , dlco , spirometry , supine position , pulmonary function testing , gastroenterology , hepatology , hepatopulmonary syndrome , diffusing capacity , cardiology , lung , portal hypertension , asthma , lung function
There is no consensus on the pathogenesis and incidence of diffusion disorder in chronic liver diseases. It is supposed that the pathogenic mechanisms responsible for the reduction of diffusion capacity in liver diseases are multifactorial, including: ventilation-perfusion mismatching, diffuse interstitial pulmonary diseases and reduced transitory time in hyperperfused lung areas [1]. The increase of diffusion of oxygen molecules within dilated blood vessels during the inspiration of 100% O2 in patients with liver cirrhosis is called "diffusion-perfusion defect" or "alveolar-capillary oxygen disequilibrium" [3].