Open Accessα-tricalcium phosphate/fluorapatite-based cement - promising dental root canal filling material
Author(s) -
Abdul Kazuz,
Željko Radovanović,
Djordje Veljović,
Vesna Kojić,
Dimitar Jakimov,
Tamara Vlajic,
Vesna Miletić,
Rada Petrović,
Djordje Janaćković
Publication year - 2022
Publication title -
processing and application of ceramics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.326
H-Index - 15
eISSN - 2406-1034
pISSN - 1820-6131
DOI - 10.2298/pac2201022k
Subject(s) - fluorapatite , cement , simulated body fluid , root canal , materials science , dental cement , apatite , bone cement , fibroblast , composite material , chemical engineering , dentistry , scanning electron microscope , mineralogy , in vitro , chemistry , medicine , biochemistry , adhesive , layer (electronics) , engineering
?-Tricalcium phosphate/fluorapatite (?-TCP/FAp) mixed powders were prepared in order to obtain dental root canal filling cements. Different liquids for cement pastes have been investigated and the most suitable one for obtaining rheologically optimal pastes was chosen for further analysis. Morphological changes in the cement materials as a consequence of the formation of hydroxyapatite (HAp) after the immersion in a simulated body fluid (SBF), an influence on the cell viability, and final success of the filling were investigated by field emission scanning electron microscopy. Treatment of the ?-TCP/FAp mixtures in SBF at 37?C resulted in a complete transformation of ?-TCP into HAp after 10 days, while the exposure of MRC-5 human and L929 animal fibroblast cells to the cement showed complete absence of cytotoxicity. The root canal of an extracted tooth was filled with the ?-TCP/FAp cement containing 5 wt.% of FAp and relatively strong adhesion between the cement and dentine was observed after 48h. The same cement material was immersed during 10 days in SBF and after that both human and animal fibroblast cells during in vitro MTT tests showed higher cell viability compared to the control sample. These findings lead to a conclusion that the ?-TCP/FAp based cement demonstrates potential for further development towards dental cement application.