Open AccessPharmacokinetic modelling of valproate in epileptic patients
Author(s) -
Mihajlo Jakovljević,
Slobodan M. Janković,
Natalija Todorović,
Jasmina Milovanović,
Snežana V. Janković
Publication year - 2010
Publication title -
medicinski pregled
Language(s) - English
Resource type - Journals
eISSN - 1820-7383
pISSN - 0025-8105
DOI - 10.2298/mpns1006349j
Subject(s) - medicine , nonmem , pharmacokinetics , epilepsy , covariate , population , valproic acid , pediatrics , body weight , anticonvulsant , statistics , psychiatry , mathematics , environmental health
The aim of our study was to develop and use a population pharmacokinetic model for assessment of individual valproate clearance in children and young adults suffering from epilepsy.