The acute and subchronic effect of 3,4-methylenedioxymethamphetamine on body temperature in rats | Zendy

Ivan Simić | Zendy; Živorad Maličević | Zendy

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The acute and subchronic effect of 3,4-methylenedioxymethamphetamine on body temperature in rats

Author(s) -

Ivan Simić,

Živorad Maličević

Publication year - 2009

Publication title -

medicinski pregled

Language(s) - English

Resource type - Journals

eISSN - 1820-7383

pISSN - 0025-8105

DOI - 10.2298/mpns0904124s

Subject(s) - mdma , ecstasy , hyperthermia , medicine , thermoregulation , rectal temperature , anesthesia , oral administration , pharmacology , psychiatry

The consumption of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) is known to cause severe hyperthermia in humans. This is of extreme importance since ecstasy is often consumed at "rave" parties, where dancing takes place in a warm environment, which may exacerbate the effect of MDMA on thermoregulation. The present study was performed in order to evaluate the effects of single and repeated administration of MDMA on body temperature in Wistar rats.

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