Open AccessThe acute and subchronic effect of 3,4-methylenedioxymethamphetamine on body temperature in rats
Author(s) -
Ivan Šimić,
Z Malicević
Publication year - 2009
Publication title -
medicinski pregled
Language(s) - English
Resource type - Journals
eISSN - 1820-7383
pISSN - 0025-8105
DOI - 10.2298/mpns0904124s
Subject(s) - mdma , ecstasy , hyperthermia , medicine , thermoregulation , rectal temperature , anesthesia , oral administration , pharmacology , psychiatry
The consumption of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) is known to cause severe hyperthermia in humans. This is of extreme importance since ecstasy is often consumed at "rave" parties, where dancing takes place in a warm environment, which may exacerbate the effect of MDMA on thermoregulation. The present study was performed in order to evaluate the effects of single and repeated administration of MDMA on body temperature in Wistar rats.