Open AccessThe role of virus infections in the pathogenesis of type I diabetes: A case report
Author(s) -
Aniko Katona-Djurekovic
Publication year - 2007
Publication title -
medicinski pregled
Language(s) - English
Resource type - Journals
eISSN - 1820-7383
pISSN - 0025-8105
DOI - 10.2298/mpns0708397k
Subject(s) - medicine , insulitis , human leukocyte antigen , diabetes mellitus , immunology , virus , pathogenesis , type 1 diabetes , titer , immune system , family history , type 2 diabetes , antibody , antigen , virology , autoimmunity , endocrinology
Coxsackie and mumps viruses are nowadays known to be pancreatropic viruses. However, the development of insulitis after viral infection is related to the genetic factor. Type I diabetes shows an association with the HLA antigens. HLA antigens are involved in cellular immune response and in the regulation of 1 T-cell activation.
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