Open AccessPathogenic mechanisms in the development of surgical site infections
Author(s) -
Zorica Jovanović,
Milena Ilić,
Slobodan Janković
Publication year - 2007
Publication title -
medicinski pregled
Language(s) - English
Resource type - Journals
eISSN - 1820-7383
pISSN - 0025-8105
DOI - 10.2298/mpns0708343j
Subject(s) - immunology , medicine , immune system , inflammation , sepsis , septic shock , lipopolysaccharide , degranulation , pathogenesis , receptor
Surgical site infections represent a major problem in modern medicine. Bacterial survival and growth in surgical wounds depends on the effectiveness of the host defense mechanisms and on the ability of bacteria to resist these defensive mechanisms. Surgical site contamination causes cellular injury and triggers the inflammatory response.