Open AccessDamage to proximal tubular epithelial cells in type 2 diabetes mellitus
Author(s) -
Vlastimir Vlatković,
Biljana Stojimirović,
Radmila Obrenović,
S Nogić
Publication year - 2007
Publication title -
medicinski pregled
Language(s) - English
Resource type - Journals
eISSN - 1820-7383
pISSN - 0025-8105
DOI - 10.2298/mpns0706272v
Subject(s) - microalbuminuria , medicine , proteinuria , diabetes mellitus , diabetic nephropathy , endocrinology , urinary system , type 2 diabetes mellitus , creatinine , gastroenterology , nephropathy , urology , kidney
Kidney damage from diabetes mellitus is called diabetic nephropathy. At the beginning it is a functional disorder, but later it results in an irreversible damage. The aim of this research was to establish damage to proximal tubular cells in patients with type 2 diabetes mellitus, and various degrees of proteinuria by determining the urinary N-acetyl-beta-D-glucose-aminidase and gamma-glutamyl-transferase; to compare obtained results with the results in healthy examinees; to establish the correlation between these enzymes, and to investigate their sensitivity.