Open AccessC-reactive protein and cytokines in the diagnosis of neonatal sepsis
Author(s) -
Bojan Janković,
Dobrila Veljković,
Srdjan Pasic,
Zorica Rakonjac,
Dragana Jevtić,
Jelena Martić
Publication year - 2006
Publication title -
medicinski pregled
Language(s) - English
Resource type - Journals
eISSN - 1820-7383
pISSN - 0025-8105
DOI - 10.2298/mpns0612545j
Subject(s) - procalcitonin , medicine , sepsis , c reactive protein , neonatal sepsis , acute phase protein , inflammation , systemic inflammation , antibiotics , intensive care medicine , immunology , gastroenterology , microbiology and biotechnology , biology
Accurate evaluation and correct treatment of neonates for possible sepsis still represent the most challenging clinical tasks. Early diagnosis of neonatal sepsis is largely based on the measurement of serum concentrations of different mediators of systemic inflammation, as well as, on a group of proteins named acute phase reactants. Among acute phase reactants, C-reactive protein (CRP) has been the most extensively used and investigated so far.