Open AccessEffects of estro-progestagens on lipid and hormonal profiles in women with premature primary ovarian failure
Author(s) -
Maja Ivanišević,
Svetlana Vujović,
Milka Drezgić
Publication year - 2005
Publication title -
medicinski pregled
Language(s) - English
Resource type - Journals
eISSN - 1820-7383
pISSN - 0025-8105
DOI - 10.2298/mpns0506296i
Subject(s) - medicine , endocrinology , body mass index , prolactin , hypergonadotropic hypogonadism , hormone , testosterone (patch) , lipid profile , premature ovarian failure , amenorrhea , sex hormone binding globulin , estrogen , cholesterol , androgen , pregnancy , biology , genetics
Premature primary ovarian failure (PPOF) is defined as cessation of menstruation before the age of 40. Women with PPOF have hypergonadotropic amenorrhea and hypoestrogenia. The incidence of PPOF is 0.9-3%, and its etiology is multifactorial (genetic, enzyme deficit, virus infections, autoimmune diseases and idiopathic). PPOF is an independent risk factor for cardiovascular diseases. Untreated women are at higher risk for coronary disease, due to increase of total cholesterol, LDL, triglycerides and decrease of HDL. The aim of this investigation was to study effects of estro-progestagens on lipid and hormonal profiles in PPOF.: