Open AccessDiagnostic significance of synovial biopsy in patients with Reiter’s syndrome
Author(s) -
Ljiljana Pavlica,
Vujadin Tatić,
Nada Draskovic,
Dragan Nikolić
Publication year - 2003
Publication title -
medicinski pregled
Language(s) - English
Resource type - Journals
eISSN - 1820-7383
pISSN - 0025-8105
DOI - 10.2298/mpns0310403p
Subject(s) - pathology , medicine , synovitis , synovial membrane , biopsy , fibrinoid necrosis , antigen , immunofluorescence , arthritis , antibody , immunology , vasculitis , disease
Arthritis in Reiter's syndrome (RS) is a reactive synovitis associated with a localized infection of the urogenital or gastrointestinal tract with a genetic predisposition. The pathogenetic mechanisms for synovitis in RS are still unknown. Our aim was to examine some of the pathogenetic mechanisms in Reiter's syndrome looking for morphologic changes, immunoprotein deposits and microorganism antigens in synovial biopsies and to determine whether synovial biopsy is useful in diagnosis of RS.