Open AccessTubulointerstitial dysfunction in early post-transplant period
Author(s) -
Tatjana Djurdjević-Mirković,
S Curić,
S Vodopivec,
Valerija Sedlak-Vadoc,
Z Stosić,
Igor Mitić,
Dusan Bozić,
L Petrović,
Tamara Ilić
Publication year - 2003
Publication title -
medicinski pregled
Language(s) - English
Resource type - Journals
eISSN - 1820-7383
pISSN - 0025-8105
DOI - 10.2298/mpns0304113d
Subject(s) - medicine , azotemia , acute tubular necrosis , creatinine , transplantation , kidney , complication , surgery , kidney transplantation , necrosis , urology , renal function , gastroenterology
Dysfunction of a transplanted kidney may develop at any time in the post-transplant period. The aim of this study was to differentiate levels of early dysfunction of a transplanted kidney. The study included 45 examinees undergoing kidney transplantation. They were divided into four groups, in regard to length of hospitalization and post-transplant complications: group I (up to 15 days, complication-free); group II (up to 15 days, with complications); group III (up to 30 days); group IV (up to 60 days). The control group included patients undergoing abdominal surgery, without uropoetic system disorders. The following parameters were examined on a daily basis a month after transplantation on average: creatinine clearance, creatinine and urea. Statistical analysis of these parameters revealed the following levels of renal dysfunction: control group--circulatory tubular dysfunction without azotemia; group I--polyuric acute tubular necrosis; group II and group III--severe or moderately severe polyuric acute tubular necrosis and group IV--polyuric acute tubular necrosis.