Physiology of fracture healing: New aspects
Author(s) -
Djordje Gajdobranski,
Dragana Živković
Publication year - 2003
Publication title -
medicinski pregled
Language(s) - English
Resource type - Journals
eISSN - 1820-7383
pISSN - 0025-8105
DOI - 10.2298/mpns0302039g
Subject(s) - bone healing , medicine , non union , wound healing , orthopedic surgery , fracture (geology) , regenerative medicine , bioinformatics , surgery , stem cell , biology , genetics , paleontology
Skeletal system has a great regenerative potential, but it isn't the case with other tissues. Bone fracture healing includes a complex cascade of processes at cellular and biochemical levels, ending with a complete structural and functional restoration of the damaged bone. Impaired healing occurs in 5-10% of all fractures, manifesting as delayed union or non-union. Such a high incidence of impaired healing certainly presents a problem, and therefore, permanent research regarding physiology of fracture healing is justified. PHASES OF FRACTURE HEALING: In this paper we described four phases of fracture healing. They are not clearly separated, but overlap. These data are based on contemporary literature and newest achievements in the field of fracture healing.
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