Open AccessImmunoglobulin A nephropathy and its prognostic factors
Author(s) -
L Petrović,
S Curić,
Igor Mitić,
Dusan Bozić,
S Vodopivec,
Sakac,
Tatjana Đurđević-Mirković,
Tamara Ilić
Publication year - 2002
Publication title -
medicinski pregled
Language(s) - English
Resource type - Journals
eISSN - 1820-7383
pISSN - 0025-8105
DOI - 10.2298/mpns0212517p
Subject(s) - medicine , proteinuria , renal biopsy , nephropathy , renal function , biopsy , kidney disease , gastroenterology , pathology , incidence (geometry) , stage (stratigraphy) , glomerulonephritis , kidney , endocrinology , paleontology , physics , diabetes mellitus , optics , biology
Immunoglobilin A nephropathy (IgAN) is a clinicopathological entity characterized by diffuse glomerular mesangial deposition of IgA as the predominant immunoglobulin. Renal biopsy reveals a spectrum of changes in glomerula, tubulointerstitium and blood vessels. 20-50% of all patients develop end-stage renal failure 20 years after onset of disease. The aim of this study was to investigate the incidence of IgAN and to analyze clinicopathological changes and prognosis of IgAN.