Synthesis of 2-azetidinones substituted quinoline derivative | Zendy

Uday C. Mashelkar | Zendy; Mukesh S. Jha | Zendy; Beena U. Mashelkar | Zendy

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Synthesis of 2-azetidinones substituted quinoline derivative

Author(s) -

Uday C. Mashelkar,

Mukesh S. Jha,

Beena U. Mashelkar

Publication year - 2012

Publication title -

journal of the serbian chemical society

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.227

H-Index - 45

eISSN - 1820-7421

pISSN - 0352-5139

DOI - 10.2298/jsc120617081m

Subject(s) - quinoline , acetanilide , chemistry , toluene , schiff base , derivative (finance) , base (topology) , organic chemistry , medicinal chemistry , combinatorial chemistry , polymer chemistry , mathematics , mathematical analysis , financial economics , economics

Acetanilide is converted into 2-chloro-3-formyl quinoline by reacting with DMF-POCl3 at 80-90ºC and then condensed with aromatic primary amines to give Schiff bases (3a-3c). These Schiff bases are then reacted with acid chlorides in the presence of base in toluene to give 1, 3, 4-substituted 2-azetidinones

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