Open AccessReaction of iodomethyltin(IV) compounds with (2s)-2,5-dihydro-3,6-dimethoxy-2-isopropylpyrazine
Author(s) -
Karin Dölling
Publication year - 2012
Publication title -
journal of the serbian chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.227
H-Index - 45
eISSN - 1820-7421
pISSN - 0352-5139
DOI - 10.2298/jsc111215007d
Subject(s) - elemental analysis , chemistry , medicinal chemistry , reaction conditions , carbon 13 nmr , nuclear chemistry , organic chemistry , catalysis
Following the Schöllkopf methodology the reaction of (2S)-2,5- dihydro-3,6-dimethoxy-2-isopropylpyrazine 1 with iodomethyl trimethylstannane gives (2S,5S)-2,5-dihydro-3,6-dimethoxy-5-trimethylstannylmethyl-2- isopropylpyrazine 2 in good yields. The obtained compound was characterized with elemental analysis and multinuclear (1H, 13C and 119Sn) NMR spectroscopy