z-logo
open-access-imgOpen Access
A regioselective alkylation at the C-6 hydroxyl group of erythromycin A-oxime derivatives
Author(s) -
Hosang Master,
Singh Dharmendra
Publication year - 2005
Publication title -
journal of the serbian chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.227
H-Index - 45
eISSN - 1820-7421
pISSN - 0352-5139
DOI - 10.2298/jsc0510147m
Subject(s) - regioselectivity , oxime , chemistry , alkylation , erythromycin , group (periodic table) , substrate (aquarium) , medicinal chemistry , organic chemistry , antibiotics , catalysis , biochemistry , oceanography , geology
Erythromycin A contains five hydroxyl groups. The regioselective alkylation at the C-6 hydroxyl group was achieved to an extent of more than 97 % when a 9-O-substituted erythromycin A-9-oxime was employed as the substrate.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here