Open AccessApplication of the log k pair linearity rule and proportionality rule to the RPP mobile phase scales estimation on cyano-silica column
Author(s) -
T.J. Janjić,
Gordana Vučković,
Milenko Celap
Publication year - 2001
Publication title -
journal of the serbian chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.227
H-Index - 45
eISSN - 1820-7421
pISSN - 0352-5139
DOI - 10.2298/jsc0103173j
Subject(s) - linearity , acetonitrile , methanol , chemistry , solvent , analytical chemistry (journal) , thermodynamics , mathematics , chromatography , physics , quantum mechanics , organic chemistry
On the basis of literature-reported log k values, the Log k pair linearity rule and the Proportionality rule were found to be also valid in the case of cyano-silica sorbent, whenmethanol, acetonitrile or propane-2-olwere used as modifiers. The RPPscales, reflecting the solvent strength, are in good linear relationship with the experimentally determined log k values. Furthermore, in the case of methanol and acetonitrile, the linear dependence: log k = f(mol%of modifier) was also established. In the function obtained in a such way, the intercept and the slope exhibit an approximate linear dependence. Finally, in the case of methanol, the experimentally obtained log k values are in a satisfactory agreement with the values calculated by the above equation.